AUTOPATHY TREATMENT REVERTS BACK DOWN SYNDROME

DOWN SYNDROME IS USUALLY CAUSED BY THE PRESENCE OF AN EXTRA COPY OF CHROMOSOME 21 [TRISOMY 21]. CLINICALLY FEATURES OF CHILDREN WITH DOWN SYNDROME INCLUDE GROWTH RETARDETION, VARYING DEGREES OF MENTAL RETARDATION, CRANIOFACIAL ABNORMALITIES – INCLUDING UPWARD SLANTING EYES, EPICANTHAL FOLDS, FLATTENED FACIES AND SMALL EARS, CARDIAC DEFECTS AND HYPOTONIA. IN 95% OF CASES THE SYNDROME IS CAUSED BY TRISOMY 21 DUE TO MEIOTIC NONDISJUNCTION, AND IN 75% OF THESE INSTANCES NONDISJUNCTION OCCURES DURING OOCYTE FORMATION. FURTHERMORE, WOMEN OVER 35 YEARS HAVE A GREATER RISK OF HAVING AN AFFECTED CHILD.

IN APPROXIMATELY 4% OF CASES OF DOWN SYNDROME THERE IS AN UNBALANCED TRANSLOCATION BETWEEN CHROMOSOME 21 AND EITHER OF CHROMOSOMES 13,14 OR 15. THE FINAL 1% IS DUE TO MOSAICISM RESULTING FROM MITOTIC NONDISJUNCTION. THESE INDIVIDUALS HAVE SAME CELLS WITH A NORMAL CHROMOSOME NUMBER AND SOME THAT ARE ANEUPLOID. THEY MAY EXIBIT FEW OR MANY OF THE CHARACTERISTICS OF DOWN SYNDROME, DEPENDING ON THE NUMBER OF ABNORMAL CELLS AND THEIR LOCATION.

NEURAL TUBE DEFECTS [SUCH AS SPINA BIFIDA AND ANENCEPHALY] PRODUCE ELEVETED ALFA-FETOPROTEIN [AFP] LEVEL AS DO THE ABDOMINAL DEFECTS [SUCH AS GASTROSCHISES AND OMPHALOCELE]. IN THESE CASES MATERNAL SERUM AFP LEVEL IS FOUND TO BE ELEVETED. WHEREAS IN CASE OF DOWN SYNDROME ALFA / BETA IMMUNOGLOBULINE POLYPEPTIDE FRACTIONS’ RATIO IS FOUND WELL ELEVETED, AND MAY BE USED AS A DIAGNOSTIC PRESCREENING TEST TO CONFIRM BY AMNIOCENTESIS.

DRASTIC CLINICAL IMPROVEMENT IS NOTED IF THE CHILDREN WITH DOWN SYNDROME ARE PUT ON AUTOPATHY TREATMENT = AAA THERAPY. ITS COURSE OF TREATMEMENT HAS BEEN FOUND MOST SUITABLE SUBLINGUALLY ONCE A DAY IN FRESH MOUTH CONTINEOUSLY FOR SIX MONTHS, AND BE REPEATED AT NINE TO TWELVE MONTHS INTERVALS TILL SATISFACTORY CLINICAL OUT PUT HAS BEEN FOUND. ALONG WITH THIS AUTOPATHY TREATMENT OTHER TREATMENTS SOS REQUIRED TO CHILDREN EXCEPT THE HEPATITIS –B VACCINE, ARE ALSO DONE. OTHERWISE, IF NEEDED, AAA-THERAPY IS STOPPED AND RESTARTED AFTER NINE MONTHS’ GAP.

ALONG WITH AAA AUTOPATHY TREATMENT OTHER MEDICATIONS MAY ALSO BE GIVEN IF THE PHYSICIANS SO FIND SUITABLE / NEEDED, FOR EXAMPLE, PYRITINOL, PIRACETAM, IODINE PREPARATION [LUGOL’S SOLUTION DROPS WITH MILK] AND OTHER BRAIN STIMULANTS. GLUTAMIC ACID PREPARATIONS THERAPY SHOULD NOT BE UNDERTAKEN WITH AUTOPATHY AAA-TREATMENT. HOWEVER, ANTIOXYDANTS AND VITAMINES THERAPY ARE PREFERED WITH AUTOPATHY THERAPY.

BELOW SHOWN FIGURES CLEARLY MANIFEST THE MORPHOLOGICAL DIFFERENCES DEVELOPED IN TRISOMY 21 BETWEEN ‘AFTER / WITHIN THE COURSES OF AUTOPATHY TREATMENT [FIG – 2/2005]’ AND BEFORE THE AUTOPATHY TREATMENT [FIG –1/1998]. VIVID MORPHOLOGICAL CHANGES ARE NOTICED IN 3, 13,14, 18 AND X / Y – CHROMOSOMES. CLINICALLY THE PATIENTS ARE SCARCELY DISTINGUISHABLE FROM NON-TRISOMY 21 CHILDREN.